The Church of Panagia ton Myriokefalon in the village of Myriokefala served as the catholicon of the Monastery of Panagia Antifonitria, dating back to the 11th century, which has not survived.
The Monastery was built by Ossios Ioannis Xenos and remained in operation until the early 20th century. Apart from the catholicon, the remaining buildings date back to the 18th and 19th century.
The catholicon belongs to the architectural style of free cross with dome. There are two layers of murals in the church, one dating back to the 11th and the other to the 13th century. The icon of the Virgin Mary in the church is considered miraculous.
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